Advances in genome engineering have resulted in the generation of numerous zebrafish mutant lines.A commonly used method to assess gene expression in the mutants is in situ hybridisation (ISH).Because the embryos can be Animals distinguished by genotype after ISH, comparing gene expression between wild-type and mutant siblings can be done blinded a

Confronted with a range of methodological options, novice researchers often face the daunting dilemma of selecting a methodological route which best fits the purpose of their study.Following the decision-making process, all methodologies present HERBATINT 5N challenges which need to be explored and addressed.This paper outlines the application of d

Abstract Background Epigenetic regulators are Coffee Tables frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy.Results To define alterations in epigenetic landscapes in breast cancers, we profiled the distributions of

Abstract Home advantage in professional sports is a widely accepted phenomenon despite the lack of any controlled experiments at the professional level.The return to play of professional sports during the COVID-19 pandemic presents a unique opportunity to analyze the hypothesized effect of home advantage in neutral settings.While recent work has ex

As a spatial coordinate sensor, the touch-trigger on-machine probe is a key equipment in manufacturing that ensures machining quality, and it has played an important role in five-axis flank milling.However, in flank milling, the utilization of the deviation as a conventional indicator for quality assessment of the machining performance is incompreh